Cytomel is not a steroid, but more a of a cutting aid. It’s a synthetic form of the thyroid hormone tri-iodio-thyronine or T3, made up of a metabolite of the amino acid tyrosine and 3 iodine ions. In the body it in turn is made from another hormone, T4, which is secreted by the thyroid under influence of the pituitary hormone TSH (Thyroid stimulating hormone). If a shortage of either TSH or T4 is noted, usually doctors may opt for a replacement therapy. These days the most common prescription is synthetic T4 (synthroid), but in more severe cases of permanent thyroid dysfunction, the choice is given to Cytomel. Simply because T4 is mostly active through its conversion to T3 and T3 is 4-5 times stronger than T4 on a mcg for mcg basis.
In bodybuilding circles Cytomel is mostly used as fat-loss drug. Thyroid hormones are often referred to as the metabolic regulators of the body. High levels of T3 speed up the metabolism of an individual, allowing him to burn more calories and use calories more sufficiently. Generally ectopmorphic body-types have very high thyroid levels and in some cases a slight undiagnosed form of hyperthyroidism. Both hyper-and hypothyroidism can have severe consequences on an individual, such as goiters and other nasty stuff, so messing with your thyroid is not something I would advise to beginners. As with insulin, misuse of this compound can leave you dependent on exogenous T3 for the rest of your life (remember Frank Zane?). So some caution and research is required before putting Cytomel in your body. Generally cycles should be limited to 4-6 weeks tops, I recommend 3 and alternating cycles with 3-week cycles of clenbuterol. But most importantly, to avoid a crash or a shock to the thyroid function doses need to be built up over time and tapered off again. More so for cytomel than for any other drug in existence.
I n his book, Anabolics 2002, Bill Llewellyn says that Cytomel is not a drug to start off on, and that use of milder drugs like T4 (Synthroid) or triacana can help ease a person into the use of T3. I’m inclined to disagree here however. Triacana is weak compound and I find of little use. Its not easily found anymore and not cheap either. T4 is basically similar to Cytomel except that its weaker. Something that users normally compensate with higher doses and sends them down a similar lane as simply using cytomel. Agreed, cytomel is NOT a drug for beginners, but with adequate research, experience with diet and some self-control, I don’t see why cytomel shouldn’t be the first thyoid compound used. But for recreational users looking for a fatburner, I still suggest using clenbuterol over cytomel for all intents and purposes. Cytomel is much more powerful, but clenbuterol is a lot safer for use. The results are easier to maintain with clenbuterol as well. Negative feedback in the thyroid may decrease natural levels of T3 in the body, causing a decrease of metabolic rate after coming off a cycle of T3. That can cause a rebound effect during which a lot of weight is gained back.
F or competitive bodybuilders Cytomel is an almost unmissable aid in contest preparation, along with clenbuterol and non-aromatizing steroids such as stanazolol, trenbolone, methenolone and so forth…
Stacking and Use:
It can be stacked or alternated with clenbuterol. We usually recommend to alternate, three weeks clen with three weeks cytomel, since clen loses most of its benefits after a short period of time and using cytomel for extended time-periods will increase the risk of permanent thyroid failure. Neither drug is terribly expensive so We see no problem in this. Some opt to use them together for 3-4 weeks, and then use an over the counter ECA stack to bridge with for an equal period of time, but we’re not big fans of that. Which naturally doesn’t mean its not effective, that’s just a personal opinion. Running it for three weeks, one could choose for a schedule as follows:
25 /25 /25 /50 /50 /50 /75 /75 /75 /100 /100 /100
/75 /75 /75 /50 /50 /50 /25 /25 /25 mcg/day.
If taken for 4 weeks, then run each dose for 4 days, 5 weeks then each dose for 5 days and so on. It is extremely important that the doses are tapered on and off and that a cycle never exceeds 6 weeks at the most.
As far as adding products, no ancillaries are needed, but its highly recommended that this is only used when anabolic/androgenic steroids are also being used. First of all the extra free calories work with the steroids to enhance results, but also because an increased level of thyroid hormones can be extremely catabolic and the use of anabolic compounds to counter muscle loss is a requirement here.
Cytomel® (liothyronine sodium)
Cytomel® is the popularly recognized brand name for the drug liothyronine sodium. This is not an anabolic steroid but a thyroid hormone. It is used medically to treat cases of thyroid insufficiency, obesity, certain metabolic disorders and fatigue. Specifically this drug is a pharmaceutical preparation of the natural thyroid hormone triiodothyronine (T-3). When administered, Cytomel® increases the patient’s metabolism. The result is an increased rate of cellular activity (noted by a more rapid utilization of carbohydrates, fats and proteins). Bodybuilders are particularly attracted to this drug for its ability to burn off body excess fat. Most often utilized during contest preparation, one can greatly decrease the amount of stored fat without being forced to severely restrict calories. To this end Cytomel® is commonly used in conjunction with Clenbuterol and can produce extremely dramatic results. This combination has become very popular in recent years, no doubt responsible for many “ripped” on-stage physiques. It is also noted by many that when thyroid hormones are taken in conjunction with steroids, an increased anabolic effect can be seen (noticeably greater than if the steroids are used alone). This is likely due to faster utilization of proteins by the body, increasing the rate for new muscle accumulation.
One should take caution if considering using this drug. Cytomel® comes with an extensive list of warnings and precautions which are not to be ignored. Side effects include, but are not limited to, heart palpitations, agitation, shortness of breath, irregular heartbeat, sweating, nausea, headaches, and psychic/metabolic disorders. It is a powerful hormone, and one that could potentially alter the normal functioning of the body if misused. When administering Cytomel®, one must remember to increase the dosage slowly. Generally one 25mcg tablet is taken on the first day, and the dosage is thereafter increased by one tablet every three of four days for a maximum dosage of 100mcg. This will help the body adjust to the increased thyroid hormone, hopefully avoiding any sudden “shock” to the system. The daily dose is also to be split evenly throughout the day, in an effort to keep blood levels steadier. Women are more sensitive to the side effects of Cytomel® than men, and usually opt to take no more than 50mcg daily.
It is important to stress that a cycle should last no longer than 6 weeks and it should never be halted abruptly. As slowly as the dosage was built up it should also be lowered, one tablet every 3-4 days. Taking Cytomel® for too long and/or at too high a dosage can result in a permanent thyroid deficiency. After doing such, one might need to be treated with a drug like Cytomel® for life. It is also a good idea to first consult your physician and have your thyroid function tested. An undiagnosed hyperfunction would not mix well with the added hormone. An athlete should also be sure never to purchase an injectable form of the drug. It is generally an emergency room product, much too powerful for athletic use. Since T-3 is the most powerful thyroid hormone athletes are using, this is generally not the starting point for a beginner. Before using such a powerful item, it is a good idea to become familiar with a weaker substance. The highly popular Triacana is very mild, allowing the user much more latitude (from severe side effects) than Cytomel®. An in-between point is Synthroid (synthetic T-4), still weaker in action than Cytomel®. Once the user is ready however, the fat burning effect of this hormone can be extremely dramatic.
On the black market, Cytomel® is readily available. 100 tablets (50 mcg) will sell for approximately $50. This price is considerably reduced when purchasing this drug from a variety of mail-order sources. Even lower in price is the Cynomel brand in Mexico. The pharmacy price for 100 25mcg tablets is only a few U.S. dollars.